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About Us

Since its inception in 2011, Wyzer Biosciences has been offering sequencing services to its partners and collaborators, supporting them in their research. We servce the sequencing needs of local, domestic and international customers. Our service includes Precision Sanger Sequencing™, next generation sequencing, DNA preparation, and genotyping. At Wyzer Biosciences, we continually refine our techniques and with 120 years of combined experience, we are ideally suited for solving your simple or complex sequencing needs.

+001 617 945 9697 OR info@wyzerbio.com

Services Details


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Offering a Wide Range of Sequencing Services

We provide Sanger Sequencing using ABI 3730xl machines. Sequencing reactions are typically run the same day our lab receives the sample. For customers utilizing our local pickup and delivery services, the lab will receive your samples the same day.

Clients may premix or send their own primers, but for partners who are comfortable sharing reference sequences with us, we order or select the appropriate primers for sequence from our inventory of 60,000+ oligos to reduce our partner’s workload.

Our Advantage

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  • Simple online ordering submission
  • Daily local sample pickup
  • Excellent customer support
  • Rapid turnaround time. Raw data Sanger orders are completed within 12 hours. Large scale DNA preps are completed within 2 weeks. NGS orders are completed 1-7 days.

Service Details

Our fleet of NGS machines include Illumina's Miseq and NextSeq, Complete Genomics's G99, and Oxford-Nanopore's MinION (see Single Molecule Sequencing (linked)). Our NGS services cater to the needs of each specific client, but our lab is particularly suited to the sequencing of targeted genes, small genomes, amplicons, metagenomics samples, and antibody screening.

  • DNA Sanger Sequencing

    Over the years, we have honed our sequencing protocals at all stages. Our experience has enabled us to handle difficult templates and solve problems faced by our clients. We offer a full range of services>

    • Raw, pre-mixed or pre-set runs
    • Fully finished sequencing confirmation
    • Novel sequencing
    • Sequence screening
  • Next Generation Sequencing

    Wyzer Biosciencess is specialized in NGS based on Illumina and Complete Genomics' SBS technology and Oxford Nanopore single-molecule sequencing. Our fleet of Illumina MiSeq and NextSeq instruments (Complete Genomics DNBSFQ-G99, Oxford Nanopre MinION and PromethION) allows us to perform rapid sequencing for:

    • Targeted genes
    • Small to large genomes
    • Full Plasmids(PlasmidSimple™, Plasmid-FS%trade;)
    • Amplicons
    • Metagenomics samples
    • Antibody screening
  • DNA Preparation

    We use well-known DNA prep kits with option of Endotonxin-free. Our DNA transformation uses electrocompetent or chemically competent E coli cells. Sequencing confirmation for Midi to Giga preps are done with Nanopore. Sanger and restriction digestion analysis are available for additional charge. Starting material includes

    • Colony
    • Agar stab
    • Culture
    • Glycerol Stock
    • Plasmid
    • Colony
  • Single-Molecule Sequencing

    Our Plasmid-FS™ and Plasmid-Simple™ pipelines, which use Oxford-Nanopore Technologies sequencing, allow clients to obtain full-plasmid sequencing data faster and often at a lower price point.

  • Molecular Biology Service

    To accelerate our customer’s projects, we provide a variety of adjacent molecular biology services, including DNA and RNA extraction, Normalization, Restriction Enzyme Digests, cDNA synthesis, PCR, and Exo-CIP™.

  • Custom Protocol

    For partners with specific needs outside the scope of our current services, we are happy to work together to develop a custom pipeline. Please contact us directly with custom protocol requests..

  • Sequence Finishing Confirmation

    Wyzer Biosciences provides the following finishing and confirmation services

    • Basic Level
      • Manual error editing
      • Possible contig assembly if more than one read is performed for each sample
      • No detailed report is provided,only a general description.
    • Advanced Level
      • Error correction in assembled contigs and comparison to the provided references
      • Possible contig assembly if more than one read is performed for each sample
      • Custom design primers, apply specific sequencing chemistry to resolve potential issues caused by DNA quality/quantity.
      • Provide detailed description of each sequencing sample, e.g. "Comparing to reference sequencing, sample has full double-stranded coverage between indicated regions without mutations"
    • Sophisticated Level
      • All services in Advanced level
      • Vectors with two or more identical repeats longer than two good quality reads on an ABI instrument.
      • Templates with >85% GC-content, long di- or tri-nucleotide repeats, AAV ITRs, mRNA long ploy A tail and long repeats.
    • Single Molecule Confirmation (New for PlasmidSimple ™ and Plasmid-FS ™)
      • Monitor various frequency mutations.
      • Useful when combined with Level 3 service.

Our Services

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